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5.1 Pharmaceuticals

Identification and development of pharmaceutical small molecules, therapeutic vaccines, antibodies and hormones including

  • drug screening and development of delivery systems
  • mechanism of action including side effects and drug resistance
  • pharmacogenetics, prediction of genetic variation and responses to drugs
  • testing in in vitro and in vivo model systems

In general this code should be used to characterise therapeutic targets rather than for their initial identification. It includes mechanism of action but should not be used to code studies where agonists or inhibitors are used as part of the methodology to understand the mechanism of other systems.

Includes mechanism of action and resistance to therapeutics. This includes characterisation of antibiotic resistance genes and mechanisms in bacteria which should not be coded as 2.2 Physical risks for cause of disease.

Includes studies predicting responses to therapies.