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UKCRC Health Research Classification System

Metabolic and endocrine

Main inclusion criteria

Metabolic disorders (including Diabetes) and normal metabolism and endocrine development and function. This includes all research on the pineal, thyroid, parathyroid, pituitary and adrenal glands.


Advice on health categories

This category includes basic studies of metabolism but not generic signalling pathways involving kinases.

This includes studies of metabolic regulation – the means by which nutrients are converted into energy – and the conditions which affect the ability of these processes to be carried out. For example regulation of blood lipids and cholesterol are classified as Metabolic and Endocrine.

Studies on nutrition, diet and obesity and/or physical activity and exercise are context based and should only be coded as Metabolic if they relate to metabolism.

e.g. diet and exercise interventions specifically aimed at reducing cholesterol levels.


This category also includes normal function and disorders of the endocrine system, including pineal, thyroid, parathyroid, pituitary and adrenal glands, and most hormones and hormone receptor studies. There are however some notable exceptions:

  • Studies of reproductive hormones, including their role in fertility, menstruation, pregnancy and menopause, are usually coded as Reproductive Health and Childbirth and not Metabolic. Studies relating to the development of male and female reproductive organs should be coded as Renal and Urogenital.
  • Studies of the pancreas and its role in metabolism, including regulation of blood sugar and Diabetes, should be coded as Metabolic. Studies of the pancreas and its role in digestion, including pancreatic juices, should be coded as Oral and Gastrointestinal.
  • Studies of the hypothalamus and its role in metabolism should be coded as Metabolic. Studies of the hypothalamus as part of the brain and central nervous system should be coded as Neurological.


Official terminology

Full name of category

Short name Unique ID
Metabolic and endocrine Metabolic



Related external links

International Classification of Diseases (ICD 10 v2016) – Chapter IV:   Endocrine, nutritional and metabolic diseases (E00-E90)