6.7 Physical
Main inclusion criteria
Testing and evaluation of physical interventions in humans in a clinical, community or applied setting including:
- physical therapies, physiotherapy, occupational therapy, speech therapy, dietetics, osteopathy and exercise
Advice on research activities
Includes physical therapies such as temperature and increased oxygen levels.
Excludes studies of nutritional supplements which should be coded as 6.1 Pharmaceuticals.
Official terminology
|
Full name of code |
Short name | Unique ID |
| 6.7 Physical | 6.7 Physical |
HRCS_RA_6_7 |
Related external links
Common Scientific Outline (CSO) – 5.6 Complementary and Alternative Treatment Approaches
Main inclusion criteria
Application and evaluation of psychological and behavioural interventions in humans in clinical, community and applied settings including:
- phase I, II, III and IV trials
- cognitive behavioural therapy, electro-convulsive therapy, counselling, therapy and social interventions
Advice on research activities
It is difficult to develop behavioural and psychological interventions without involvement of human participants.
Use 5.6 Psychological and Behavioural for studies involving the development and testing of new behavioural therapies and psychological interventions in pre-clinical and model settings.
Examples include preliminary qualitative work (e.g. literature reviews, discussions with patients and practitioners) development of the techniques/technologies to be used in the therapy (e.g. questionnaires, computer programmes). Testing may involve human participants and still considered treatment development if few in number, involve volunteers (not patients), and/or are clearly identified as preceding formal pilot studies and clinical trials.
Use 6.6 Psychological and Behavioural for studies involving human participants in direct clinical applications.
These will typically involve both pilot studies on small numbers of patients to assess viability of new treatments, and larger phase I-IV clinical trials which formally evaluate new or modified treatments against existing procedures.
Official terminology
|
Full name of code |
Short name | Unique ID |
| 6.6 Psychological and behavioural | 6.6 Psychological |
HRCS_RA_6_6 |
Related external links
Common Scientific Outline (CSO) – 5.6 Complementary and Alternative Treatment Approaches
Main inclusion criteria
Clinical application and evaluation of interventions in humans including:
- small scale and pilot studies
- phase I, II, III and IV trials
- radiotherapy, radioimmunotherapy and radiosensitisers, microwaves, ultrasound, laser and phototherapy
- monitoring side effects
Advice on research activities
In addition to radiotherapy includes electromagnetic therapies and phototherapies.
Official terminology
|
Full name of code |
Short name | Unique ID |
| 6.5 Radiotherapy and other non-invasive therapies | 6.5 Radiotherapy |
HRCS_RA_6_5 |
Related external links
Common Scientific Outline (CSO) – 5.2 Localised Therapies – Clinical Applications
Main inclusion criteria
Clinical and applied application and evaluation of surgical, obstetric and dental interventions in humans including:
- small scale and pilot studies
- phase I, II, III and IV trials
- procedures including organ and bone marrow transplantation, tissue grafts and transfusions
- monitoring outcomes, side effects and rejection
Advice on research activities
Includes invasive mechanical procedures.
Official terminology
|
Full name of code |
Short name | Unique ID |
| 6.4 Surgery | 6.4 Surgery |
HRCS_RA_6_4 |
Related external links
Common Scientific Outline (CSO) – 5.2 Localised Therapies – Clinical Applications
Main inclusion criteria
Application and evaluation of medical devices in humans in a clinical, community or applied setting including
- implantable devices, mobility aids, dressings, medical equipment and prostheses
- validation of design and post market surveillance
Official terminology
|
Full name of code |
Short name | Unique ID |
| 6.3 Medical devices | 6.3 Devices |
HRCS_RA_6_3 |
Main inclusion criteria
Clinical application and evaluation of cellular, tissue and gene therapies in humans including:
- small scale and pilot studies
- phase I, II, III and IV trials
- gene therapy, stem cell therapy, in vitro fertilisation, tissue engineering
- evaluation of applied delivery systems
Advice on research activities
This code is suitable for studies involving stem cell therapies, particularly tissue regeneration or repair of damaged tissue, in clinical and applied settings.
Cell therapy can often involve a transplantation process but they should not be coded as 6.4 Surgery too. An exception to this is surgical transplantation of bone marrow stem cells for cancer treatment, which is considered a similar process to organ transplantation, and should therefore be coded as 6.4 Surgery.
Excludes basic developmental biology of stem cell fate which should be coded as 1.1 Biological.
Official terminology
|
Full name of code |
Short name | Unique ID |
| 6.2 Cellular and gene therapies | 6.2 Cell and gene therapy |
HRCS_RA_6_2 |
Related external links
Common Scientific Outline (CSO) – 5.4 Systemic Therapies – Clinical Applications
Main inclusion criteria
Clinical application and evaluation of pharmaceutical small molecules, therapeutic vaccines, antibodies and hormones in humans including:
- small scale settings and pilot studies
- phase I, II, III and IV trials
- assessing sensitivity, efficacy, specificity, relapse, survival, therapeutic value, pharmacokinetics, reproducibility and safety
- studies monitoring response, outcome, drug resistance and side effects
Advice on research activities
Includes studies of nutritional supplements used as treatments for disease.
Excludes studies focused on the potentially chemopreventative / health protective effects of specific nutrients, probiotics and nutritional supplements, which should be coded 3.3 Nutritional Prevention.
Official terminology
|
Full name of code |
Short name | Unique ID |
| 6.1 Pharmaceuticals | 6.1 Pharmaceutical |
HRCS_RA_6_1 |
Related external links
Common Scientific Outline (CSO) – 5.4 Systemic Therapies – Clinical Applications
Main inclusion criteria
- development and/or distribution of resources for general use by the research community including equipment, cell lines, tissue and DNA banks
- infrastructure support for networks, consortia and centres
Official terminology
|
Full name of code |
Short name | Unique ID |
| 5.9 Resources and infrastructure (treatment development) | 5.9 Resources |
HRCS_RA_5_9 |
Related external links
Main inclusion criteria
Discovery and development of complementary approaches to conventional medical therapies including:
- hypnotherapy, meditation, massage, acupuncture and homeopathy
- mechanisms of action
- testing in model systems
Official terminology
|
Full name of code |
Short name | Unique ID |
| 5.8 Complementary | 5.8 Complementary |
HRCS_RA_5_8 |
Related external links
Common Scientific Outline (CSO) – 5.6 Complementary and Alternative Treatment Approaches
Main inclusion criteria
Development of physical interventions including:
- physical therapies, physiotherapy, occupational therapy, speech therapy, dietetics, exercise and osteopathy
- mechanisms of action
- testing in model systems
Advice on research activities
Excludes studies of nutritional supplements which should be coded as 5.1 Pharmaceuticals.
Official terminology
|
Full name of code |
Short name | Unique ID |
| 5.7 Physical | 5.7 Physical |
HRCS_RA_5_7 |
Related external links
Common Scientific Outline (CSO) – 5.6 Complementary and Alternative Treatment Approaches