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UKCRC Health Research Classification System

Cerebral palsy and spina bifida

Advice on health categories

Cerebral palsy is a neurological disorder which can be acquired as a result of conditions in pregnancy, birth or childhood and is therefore coded as Neurological and not Congenital Disorders.

Spina bifida is a developmental birth defect involving the neural tube and is usually coded as Neurological.

 

Main inclusion criteria

Dementias, transmissible spongiform encephalopathies, Parkinson’s disease, neurodegenerative diseases, Alzheimer’s disease, epilepsy, multiple sclerosis and studies of the normal brain and nervous system.

 

Advice on health categories

This category is suitable for studies of the ‘wiring’ of the brain.

Includes studies of TSEs, CJD and prion protein.

Studies on circadian rhythm are often but not always Neurological.

Other conditions where disruption to circadian rhythm is linked to disease should be coded to the appropriate health category. For example, circadian influence on immune cells in rheumatoid arthritis would be coded as Inflammatory and Immune System.

Studies on headaches and migraine are often but not always Neurological.

Headaches resulting from other conditions may require alternative or additional health categories, following the rules for sequelae. For example, headaches resulting from visual impairments can be coded 50% Eye, 50% Neurological.

Studies of the Blood-Brain Barrier, vascular cognitive impairments and vascular dementia should be coded as Neurological unless there is significant additional emphasis on either circulation (50% Cardiovascular, 50% Neurological) or the blood flow to the brain (50% Neurological, 50% Stroke).

Excludes studies dealing with the brain of individuals with a psychological condition listed in the Mental Health category which should be coded as 100% Mental Health.
 

Official terminology

Full name of category

Short name Unique ID
Neurological Neuro

HRCS_HC_13NEU

 

Related external links

International Classifications of Diseases (ICD 10 v2016) – Chapter VI:   Diseases of the nervous system (G00-G99)
 

Main inclusion criteria

Physical abnormalities and syndromes that are not associated with a single type of disease or condition including Down’s syndrome and cystic fibrosis.

 

Advice on health categories

Includes physical malformation and congenital syndromes that are associated with multiple diseases and conditions.

Excludes inherited single disease disorders (even when referred to as ‘congenital’) which should be coded under the appropriate Health Category.
 

Official terminology

Full name of category

Short name Unique ID
Congenital Congenital

HRCS_HC_04CON

 

Related external links

International Classification of Diseases (ICD 10 v2016) – Chapter XVII: Congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
 

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