Foetal development, pregnancy and ‘in utero’ studies
Advice on health categories
If the subject of a study is the foetus or the new born it should be coded as Reproductive Health and Childbirth and also the condition being investigated, if relevant.
If the investigation involves examining the effects of exposure to agents in utero or more generally during pregnancy on children or adults, code the research to the condition under investigation and not to Reproduction.
e.g. potential increased risk of cardiovascular disease in adults as a result of maternal malnutrition should be coded 100% Cardiovascular.
Advice on research activities
Pregnancy is considered normal function and coded within the 1 Underpinning code group but investigation of factors impacting on pregnancy should be coded elsewhere.
Main inclusion criteria
Studies of normal biology including:
- genes and gene products
- molecular, cellular and physiological structures and function
- biological pathways and processes including normal immune function
- developmental studies and normal ageing
- bioinformatics and structural studies
- development and characterisation of model systems
Advice on research activities
To be used for research involving normal biological function including the following:
- basic immune and pain responses and wound healing studies that are not linked to a specific disease/condition stimulus
- normal ageing or pregnancy not linked to a condition
- normal stem cell research into differentiation and basic developmental biology of stem cells not linked to therapeutic development
- protein structural studies
- bioinformatics
- normal cell cycle and DNA replication and repair
Excludes studies characterising proteins or pathways linked to a condition or disease.
Excludes studies of processes associated to cancer which are rarely ‘normal’.
Official terminology
Full name of code |
Short name | Unique ID |
1.1 Normal biological development and functioning | 1.1 Biological |
HRCS_RA_1_1 |