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UKCRC Health Research Classification System

Foetal development, pregnancy and ‘in utero’ studies

Advice on health categories

If the subject of a study is the foetus or the new born it should be coded as Reproductive Health and Childbirth and also the condition being investigated, if relevant.

If the investigation involves examining the effects of exposure to agents in utero or more generally during pregnancy on children or adults, code the research to the condition under investigation and not to Reproduction.

e.g. potential increased risk of cardiovascular disease in adults as a result of maternal malnutrition should be coded 100% Cardiovascular.


Advice on research activities

Pregnancy is considered normal function and coded within the 1 Underpinning code group but investigation of factors impacting on pregnancy should be coded elsewhere.


Main inclusion criteria

Studies of normal biology including:

  • genes and gene products
  • molecular, cellular and physiological structures and function
  • biological pathways and processes including normal immune function
  • developmental studies and normal ageing
  • bioinformatics and structural studies
  • development and characterisation of model systems


Advice on research activities

To be used for research involving normal biological function including the following:

Excludes studies characterising proteins or pathways linked to a condition or disease.

Excludes studies of processes associated to cancer which are rarely ‘normal’.

Official terminology

Full name of code

Short name Unique ID
1.1 Normal biological development and functioning 1.1 Biological



Related external links

Common Scientific Outline (CSO) – 1.1 Normal Functioning